The Karlovy Vary Region (Czech: Karlovarský kraj) is an administrative unit (Czech: kraj) of the Czech Republic, located in the westernmost part of the country. It is named after its capital Karlovy Vary. It is known for spas, which include Karlovy Vary and Mariánské Lázně. The Karlovy Vary Region, as a higher territorial self-governing unit, was created in 2000 in the northern part of the West Bohemian Region. The seat of the region is Karlovy Vary. In terms of size, number of municipalities, and population, it ranks among the smaller regions of the Czech Republic. Its area (3,314 km²) covers 4.25% of the territory of the Czech Republic. The Karlovy Vary Region is the third smallest region by area, right after Prague and the Liberec Region. By population, the Karlovy Vary Region is the smallest region in the Czech Republic, with approximately 279,000 inhabitants. (from Wikipedia)