Malignant tumors are complex ecosystems formed in addition to malignant cells and supporting cells, which significantly affect the growth of most tumors. In oncology, efforts to intervene directly in tumor cells are dominated. Therapeutic intervention in the supporting component of the tumor ecosystem, however, can also have major impacts on malignant cells. In the proposed project, we will design substances for possible innovative oncological therapy. The research team has so far received over 70 relevant patents, including international. a.