The aim of the project is to increase the research potential and international excellence of the research centre in the development of new technologies and validation of in vitro toxicological procedures using cell and organ cultures derived from tissues of human origin instead of animal experiments. Interdisciplinary research will focus on the pathways of harmful effect (AOP) of chemicals, biocides, nanomaterials and other components of products intended for consumers, including vulnerable population groups (e.g. children, seniors).