THE WORK PROPOSED BY COEPIE DECODIFICHERIS THE ENVIRONMENTAL CHANGES, METABOLIC RISK FACTORS AND ENDOFEEPI THAT COULD CAUSE EPIGENETIC CHANGES BY ALTERING THE FUNCTION OF SHARED GENES AND ENCOURAGING THE DEVELOPMENT TOWARDS CANCER AND THE DEVELOPMENT TOWARDS CANCER AND COMORIBITTS, IDENTIFYING THE GENETIC AND EPIGENEIC VARIATIONS ASSOCIATED WITH PHENOTYPES AND INTERROGANDONE THE ASSOCIATION. IN PARTICULAR, THE DIRECTOR ON WHICH THE PROJECT IS USING ÃO REPRESENTED BY THE TRAJECTORY ERA/METABOLIC DISORDERS/EPIGENETICS/NEOPLASTIC PHENOTYPE WITH THE METABOLIC ONE. THE ELEMENT CHARACTERISING THE SCIENTIFIC TRAJECTORY OF COREPIC Ê CLARIFICATION OF THE COMPLEX ASSOCIATION OF SOME FORMS OF CANCER (PANCREAS, LIVER, COLORECTAL, BLADDER AND BREAST) AND THE CURRENT EPIDEMIC OF OBEBI AND DIABETES.