The U21-REPROREG project includes a wide range of activities aimed at improving the quality of teaching, developing graduates’ output competences and expanding the offer of study programmes, increasing the professional competence of academic staff, reducing study failures and increasing interest in university studies and efficiency of management processes at UJEP, all with emphasis and binding on the goal of contributing maximum to the development of the Ústí Region and solving its existing problems as a structurally affected region.