THE PROJECT AIMS TO OVERCOME TECHNOLOGICAL PROBLEMS IN THE DEVELOPMENT OF NEW DIAGNOSTIC AND THERAPEUTIC STRATEGIES FOR DISEASES WITH A HIGH SOCIAL IMPACT, SUCH AS MELANOMA AND MULTIPLE SCLEROSIS. THE IDEA IS BASED ON THE DEVELOPMENT OF NEW TECHNIQUES FOR CELL ENGINEERING AND/OR SELECTIVE TARGETING BY NANOCARRIER AND FOCUSES ON THE USE OF THE OWN MULTIMODAL PROPERTIES OF THESE CONSTRUCTS, THEIR ACCUMULATION IN THE TISSUES D? INTEREST, OR FOR SELECTIVE RECOGNITION OF TARGETING OR INTERNALISATION IN CELLS OF THE IMMUNE SYSTEM, THEIR ABILITY TO OPERATE AS LAW ENFORCEMENT AGENTS FOR IMAGING AND TO BE OPERATED BY LOW FREQUENCY MAGNETIC FIELDS AND/OR LASER PULSES, FUNCTIONING OF THE IPERTERMBICI MEDIATORS. IN THE LAST FEW YEARS, ERCOL HAS MADE PROGRESS IN OVERCOMING THE STATE OF THE ART, DEVELOPING AN INNOVATIVE TECHNIQUE, WHICH CAN BE CUSTOMISABLE ON THE INDIVIDUAL PATIENT AND WHICH IS APPLICABLE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES WITH A REMARKABLE SPECIFICATION FOR SEVERAL DISEASES. IN THE PRESENT