Reference_Aid_programme: SA.41471(2015/X) Purpose_public_aid: Article 25 of Regulation (EC) No 651/2014 of 17 June 2014 declaring certain categories of aid compatible with the internal market in application of Articles 107 and 108 of the Treaty (OJ Urz. EU L 187/1 of 26.06.2014). The aim of the project is to develop and implement a technology platform by generating modular chemicals capable of protein degradation depending on the biological context, e.g. the type of disease or the organ in which it occurs. The applicant identified a market need and verified the pharmaceutical industry’s demand for small-molecular chemicals for new ligas ubiquitin E3 with organ, tissue, cell and disease specificity. The project’s proof of concept will demonstrate the ability to degrade selected proteins in different cell types and cell compartments. The selected chemical compounds that build the platform will be produced grammatically as part of the development work and will then be patented and will be a ready-to-sell degrading platform that will allow the licensee to intentionally degrade proteins, which will significantly reduce the amount of side effects resulting from the nature of the therapeutic approaches currently used.