The I-ADAPT project is an interdisciplinary investigation of the problem of rising Mediterranean temperature and biological invasion, both components of climate change in the Mediterranean basin. I-ADAPT aims to study the adaptation of the alien marine manifestoHalophila stipulacea in the Mediterranean and to explore the role of heating in facilitating the spread of the species. The expected warming in the Mediterranean may favour the spread of H. stipulacea due to its tropical/subtropical origin, which may give the alien species a competitive advantage over the indigenous species Posidonia oceanica and Cymodocea nodosa. The objectives of the project will be achieved through an interdisciplinary approach, which will include the combination of ecological and environmental data with genomic and proteomic data from populations derived from the natural biogeographical distribution of H. stipulacea (Red Sea) and populations from areas along the natural temperature variation observed in the Mediterranean basin (Cyprus, Greece, Italy), which is the target area of the project.