The project concerns the Central Unit of the Region of Western Macedonia created by the partnership of the Centre for the Treatment of Dependants (KETHEA) and the Organisation Against Drugs (OKANA) will carry out interventions of the following types:- Update the target group of Prevention Centres on specific issues of dealing with dependence. — References from the Centres for Prevention of persons whose type or gravity of dependence does not favour their treatment by the Centres. — Support of the Centers for Prevention in matters of mental and physical health based on networking with Health Services. Western Macedonia will operate in a network with the existing Anti-dependencies Services in the Region as well as with other health/social care structures (Hospitals, Health Centres, Mental Health Centres, Municipal Social Services, Social Clinics, etc.). In addition, it will also work with Services involved in the overall confrontation of the problem of dependence such as Training Services, Judicial Services, Correctional Branches, etc.