Selected alpha-helicoid proteins will form the basis of a technological platform for the creation of bio-inspired materials (fibres and hydrogels). These biocompatible materials will be formed by polymerisation of specially designed protein scaffolding, in which it will be possible in a second stage to connect a vast variety of enzymatic domains. These will give biomaterials selected functionalities. The possibility of a flexible combination of various territories in scaffolding will allow the conversion of fibrils/hydrogels into active biological agents, even those not present in natural biomolecules, creating potential applications in biomedicine (e.g. gene therapy) in plant biotechnology (e.g. modification of metabolic pathways), the “green” chemistry, etc. The production of new biomaterials is based solely on biological methods, with low production costs and minimal environmental burden.