However, the start of the COVID-19 pandemic hit most of the unprepared countries, and it took a relatively long time in Slovakia to run the test system and it was possible to quickly identify the infected and then secure the appropriate form of quarantine. At the time of the submission of the project, we registered more than 25 million infected patients worldwide and over 800,000 patients succumbed to the disease. In Slovakia it is as of 27.8. 2020 3626 positive test subjects, of which 420 actively ill and the disease have been affected by 33 patients so far. These low numbers for Slovakia compared to other countries were achieved mainly thanks to the above-mentioned effective epidemiological measures, which were applied across the board. Despite the gradual improvement of the epidemiological situation following the lifting of the emergency and the opening of borders in most European countries, the number of infections is increasing and concerns about the second wave of the pandemic are increasing.Therefore, the main objective of the project is to develop and validate new methodological procedures for the diagnosis of SARS-CoV-2 and their implementation into practice. In this situation, any country with prospective innovation potential can develop methods that would help not only routine testing but also the monitoring and testing of larger groups of people (e.g. outbreaks, students, company staff, testing of residents and staff in social services homes, etc.)Rangible testing capacity, rapid case isolation and timely and effective contact tracing and their subsequent quarantine is essential to reduce the incidence of the disease to manageable levels and to prevent or limit the need for strict epidemiological interventions; At the same time, research will help us estimate the prevalence and better understand the immune system responses. In addition, the activities of the project will help us understand the actual occurrence and description of cases (especially asymptomatic) in terms of geography and demography with the possibility of subsequent modification in epidemiological measures. The project will be implemented in the research center – Martin’s Biomedical Centre (BioMed Martin) and partners of MATADOR Automation, s.r.o. and R-DAS, s.r.o. will also participate in the project by selected clinical experts, bioinformatics and part of the activity will be carried out through contract research. The project will be implemented through a main activity with several work packages, which will be complementary to the activity within the Bratislava Self-Governing Region and the activities of the industrial partners of the project. The precise description of the activities and the indicated measurable indicators will be described in the following sections of the grant application.