This is a unique initiative that will place the University of Málaga (UMA) and Andalusia among the leaders of high-performance parallel computing. The joint power of the current Supercomputing Service and Bioinformatics (SCBI) plus this platform will take us to the PetaFLOPS range, and allow then to scale up to Europe's goal in supercomputing: Exascale._x000D_ _x000D_ The shared use of the infrastructure is ensured by its installation in the SCBI at UMA, recognized as a Singular Scientific-Technical Infrastructure and node of the Spanish Supercomputing Network (RES)._x000D_ _x000D_ The proposal benefits 11 UMA groups (71 researchers), an international community already identified (200 researchers) and has the support of 16 companies. The impact is in 14 lines of research on challenges for society and creation of knowledge of excellence, supporting 4 European projects, 19 national projects, 6 Andalusian projects and 15 contracts with companies, all of them active (more than ¿ 5 million). For those projects, high-performance graphics processing units (GPUs) are indispensable: first, to extract knowledge from a large data set (TB) using AI; second, for numerical simulation, a massively parallel activity. We include Industry 4.0 and Smart Cities because they are of a huge present importance._x000D_ _x000D_ Our proposal is to connect multiple servers with 8 GPUs each, an infrastructure difficult to find, with direct future scalability (both, in processors and memory).