The main objective of this research project is to obtain diploid blastocysts heteroparentales from human unipronucleares pre-embryos. This will establish a predictive model, non-invasive and explore ploidy, the strategy of obtaining diploid blastocysts unipronucleares heteroparentales from diploid zygotes. For this purpose is proposed to develop a genomic method for identifying particular abnormal embryos at the chromosomal level, detect anomalous events of chromosome segregation (uniparental disomies and isodisomías) also allowing identifying carriers embryos, or affected, monogenic diseases, setting the phase of haplotypes The parents. Resulting in enormous clinical interest as it will shed light on the mosaicism in blastocysts and trophectoderm role in early embryonic development and its relationship with the progenitor cells that direct the next stages of cell differentiation.