E-PISA is a junior research group of TU Chemnitz in the field of microsystems for the fields of medical technology and Industry 4.0. The aim of the project is, on the one hand, to produce in vivo pressure converters for catheters that work without electrical connections, which can be highly miniaturised and are MRI-compatible. On the other hand, microsystems are to be created that allow optics for optically coherent tomography to be integrated into an endoscope head. The miniaturisation of the system enables non-invasive tissue analysis and offers the potential to partially replace biopsies. In addition, energy-saving or self-sufficient systems for structural sound monitoring of industrial plants are investigated. The intelligent sensor nodes allow increased productivity, process control and safety. These demonstrators are based on innovative microsystems based on piezoelectric converters with aluminium nitride and nanoelectronics based on carbo-nano tubes. In this project, the Faculty of Electrical Engineering and Information Technology, the Center for Microtechnologies, the Institute of Physics and the Faculty of Economics cooperate to explore innovative solutions for relevant fields of demand in the fields of industry, science and society.