The operation is based on funding obtained through the 2019 Call for Academic Interest Projects (APR IA) of the Region Centre-Val de Loire for the purchase of a confocal fluorescence microscope (MICROFLU). The CBM’s P@CYFIC platform includes large instruments using fluorescence techniques applied to biological tissues, biological fluids, cells, cellular organites, microorganisms, nanoparticles. It includes flow cytometers, fluorescence microscope videos and a confocal fluorescence microscope (MICROFLU). Because of its design and operation, P@CYFIC structures the research in biology and the chemistry/biology interface of the CBM teams that use it on a daily basis. It is open to the regional, national and international scientific community for academic laboratories or private companies. The current MICROFLU was purchased in 2006 (13 years ago) with funds from the Association Française contre les Myopathies (AFM) supplemented by CNRS funds. This microscope suffers repetitive failures at both the microscope and computer level. The “soft” and “hard” of this instrument will soon be no longer repairable. It is the only functional MICROFLU on the Grand Campus Orléanais. An important element is that this platform is managed by a CNRS engineering engineer who works on it 100 %, which guarantees the stability of the service and the proper maintenance and monitoring of this heavy equipment. [...]