With the aim of promoting the systemic link between the preservation of ecosystems and its beneficial effects on people, the project health by nature imagined on the site of a nature reserve, becomes a scientific and sensitive demonstrator. Indeed, in the face of energy, climate and environmental challenges, society as a whole must move forward in order to respond as effectively as possible to these new constraints, which are at the same time tremendous opportunities. Of course, the areas most concerned are those that depend most on energy or generate the most environmental impacts, which is particularly the case in the building sector. The environmental quality of a building is both a major concern and a constraint that needs to be incorporated into the design process. This concerns in particular the choice of constituent products and materials (which must be more environmentally friendly), but also the basic conceptual aspects related to the quality and use of the construction health and safety of the occupants, resistance to various natural factors and weather, etc. Consideration should also be given to the way in which the building (construction phase) on site, logistics for the supply of raw materials, disposal of waste, etc. should be carried out. Finally, consideration must be given to the end of life of the possible rehabilitation or deconstruction