The UFOGUIDE project aims to develop a medical device for the treatment of bone metastases in a non-invasive manner and without irradiation. This device combines High Intensity Focused Ultrasounds (HIFU) to destroy tumours in a non-invasive and non-harmful manner, and MRI imaging to control treatment in real time. It meets an important medical need because bone metastases are particularly common in breast, prostate and lung cancers, and current treatments are heavy, traumatic and costly. The device developed will be safe, effective, and reliable and will result in a reduction in the costs of dealing with these pathologies.