The Research Federation “Materials and Nanosciences of Alsace” and the Carnot MICA Institute are mobilising to contribute to the advancement of knowledge at the highest level and promote technology transfer and innovation. This site project strengthens the only regional RMT network for basic and technological research in the field of materials and laboratories involved in this network: ICS, ICPEES, lnserm/BMIT, IPCMS, IS2M, ISL-ETM, ICube D-ESSP team and ISIS. The technological challenges of the 21st century in the field of materials will depend on the progress made on the materials themselves, the control and optimisation of the implementation processes, and the fine knowledge of their properties on all scales.