The emergence of clean reactor technologies requires the development of research methods for new raw materials and processed chemicals. The aim of the PRE project is to develop and verify a method(s) that can proactively examine the functionality of chemicals and auxiliary substances used in the manufacture of bio-products even before new process solutions are dimensioned to factories. At the same time, the development and application of reliable analytical methods improves the competitiveness and market position of Finnish quality products, promotes the commercialisation of innovative process concepts and offers growing international business opportunities for specialised SMEs and service companies. Business opportunities for businesses are very significant. More efficient process solutions will provide about 50 % efficiency in the consumption of chemicals used in bio-products (cards, webable new biocomposite materials, tissue products) and energy and water. It is estimated that the precipitate of a pulp mill in biorefineries on process surfaces, in particular in filters and washing equipment, can lead to a loss of production of up to 5-10 %, as well as a significant increase in chemical and energy consumption compared to situations where new technologies and knowledge could prevent these disturbances without downtime. Precipitates are typically of calcium-oxalate origin and are based on a lack of knowledge of their origins under different process conditions, as well as of different wood raw materials and waters. If these problems are not adequately managed or prevented, then the export and development of new clean process technologies can stop or at least slow down. The project therefore generates new information for a large number of SMEs and produces and verifies intelligent methods for solving the problems prioritised by industry as technology and service businesses.