II.A. Presentation of the tasks to be realised in the course of the project The professional needs of modern neurorehabilitation can only be effectively met by the joint operation of an interdisciplinary research team and a well-established equipment park. Our goal will be to assess the recipients before therapy; muscle strength, range of joints, balance — coordination of motion, seat, position, walking, cognition, measurement and documentation of speech ability. In addition, continuous monitoring of therapy will also be important, depending on functional impairments, periodic examinations and tests will be carried out. We will also regularly evaluate the effectiveness of the therapy. Our research will include repeating examinations, tests and comparisons with initial results at the beginning of therapy. All these researches will be carried out in the framework of the Neuro-biomechanical Laboratory and the Robotic and Fine Mechanical Laboratory, divided into two major but closely cooperative groups. In the Neuro-biomechanics laboratory (responsible manager: Tamás Dóczi) we will develop and test new therapeutic methods. These will include: 3D motion therapy — we will acquire a vertical suspensive physiotherapeutic device. The tool and the relevant method are a new, untapped area for specialised research, which can be used for example for the development and analysis of 3D movements in paretic patients. With the help of virtual reality technology, the patient performs complex combinations of motion in a 3D environment “in conjunction with the game” without the need to attach a sensor or control technical unit to his body for motion analysis. The technology allows complex movement patterns to be carried out even with minimal muscle strength. These exercises favourably influence motor function, coordination and, to a lesser extent, cognitive function in neurodegenerative diseases, neuromuscular disorders and acquired brain injury. Acquisition of FES (“Functional Electrical Stimulation”) system and development of new management protocols. The aim of the development is to develop rehab technology based on FES controlled limb movements. This requires new special ergometers. It is also necessary to install new multi-channel FES muscle stimulation devices. The production of stimulation patterns corresponding to motion forms is based on the examination of intact people, the evaluation and processing of motion samples measured using motion analysis systems. We plan to set up wireless, mobile, cardiovascular and respiratory functions, parameters and analysis systems to measure the physiological parameters of patients using FES. We also set up a device for ergometric tests, as well as tools for examining the movement of joints and the effects of stimulation on the paralysed muscles (muscle mass, possibly muscle activity). Lower limb FES applications are extended for upper extremity, manual cycling. Special emphasis will be placed on FES’s brain representation and its analysis with fMRI. Human exoskeleton research: in the treatment of patients with paretic or reduced lower limb function, one of the innovative solutions of our time. With their help, both the nursing and rehabilitation phases can be completed during care. On the one hand, the aim of our research is to examine the effectiveness of the new combined rehabilitation procedures from both physiological and psychological point of view, especially taking into account the guidelines of personalised medicine. On the other hand, our goal is to observe and develop new control principles and solutions through the technical examination of the devices. During the development of the tools, the consistency of mass and the corresponding material and structural indicators is a fundamental issue, so we would like to examine these as well, in conjunction with our existing research. The indirect aim is to create compact, future-proof devices that are affordable for all. Neuroprostheses: Various limb deficiency conditions affect tens of millions of people around the world. The new neuroprostheses, operated by EEG, EMG or direct neuron control, have a large number of degrees of freedom, sophisticated motors, ensuring precise movements. In the course of our research, we plan the acquisition, testing and integration into rehabilitation of the equipment currently available. Our objective is to produce individualised and highly functional prostheses of limbs in a cost-effective way, based on innovative manufacturing processes. In the examination of neuroprostheses, the question of the control of devices (signal recording and signal transmission and processing) is a priority, which can lead to the development of new methods for the development of body surface and intramuscular control principles. Human exoskeletons and neuroprostheses are general te