This project provides for the development of a Centre of Expertise (CoE) Smart Sustainable Manufacturing (S2M) that creates a sustainable structure linking education, applied research at HBO level and the demand of technical SMEs (making industry). The approach of the CoE S2M is to create a breeding ground for an appropriate educational offer (e.g. training courses, (upskilling pathways, hybrid teachers and flexible learning routes) from demand-driven research from companies together with professionals and students. In this way, education and thus the current and future labour market are better aligned and structurally linked to practice. This leads to more appropriate qualified professionals for the regional labour market. The Northern Netherlands is currently developing rapidly in the field of High Tech Systems &Amp; Materials and Smart Industry. There are several (icon) projects with (inter)national appearance: Region of Smart Factories, WCCS and ID3AS. Added in Emmen is the first Smart Shared Facility in the Netherlands and recognised Fieldlab. With these projects, public and private parties jointly invest heavily in a regional knowledge position for the North Netherlands. What is missing at the moment is a landing point for the assurance of the knowledge gained from these and other projects. Partly through a CoE S2M and the knowledge campus NHL Stenden and ADDED Emmen can form such a landing spot. A place where the connection can be made with knowledge gained from existing lecturers, such as NHL Stenden’s assistants in Leeuwarden in the field of Computer Vision and Data Science. The CoE S2M aims to be the hub of knowledge and expertise, in the fields of Technical Informatics, Polymer Engineering and Mechanical Engineering, within a Northern HTSM community. The content focus is on the following Smart Manufacturing themes: Model Based Engineering, Added Manufacturing, Robotics &Amp; End-of-Arm Tooling, Smart Systems, Smart Industrial Control & Sensor Applications. These themes fit seamlessly with the ongoing Smart Industry knowledge development projects in which NHL Stenden is involved. This also responds to the need to support the regional labour market and businesses in their further development on the high-tech systems ladder. The approach of the CoE is to create a breeding ground for an appropriate educational offer from practical research, based on the principle of regional co-makership: in the region, for the region and in triple helix. In this way, through demand-driven research, education and thus the future and current labour market is more structurally linked to practice. By its positioning between education and business, the CoE S2M aims to accelerate the circulation of knowledge and to connect supply and demand in a structural way with the region. For the purpose of the desired knowledge offer, the CoE works closely with CoE S2M Partners. They form the sounding board group and are important for the design and content of the CoE. They are the regional leaders on the chosen Smart Factory themes and are willing to invest risk-bearingly in promoting the regional learning culture by experimenting with the CoE on alternative forms of learning. The CoE S2M Partners are: Stevens Engineering, Dopple, kxa, GeTech and UG. A CoE business platform is being set up to create a sustainable structure for demand articulation. Initially, the business platform is formed from members of the business associations Techniek Socïeteit, the 3D metal print cluster, Technologies ADDED, EMMTEC Industry &Amp; Businesspark and ENGIE. However, the collaborative structure is open and scalable in which interested companies can join the business platform during the project and beyond. The operation of the CoE S2M is based on knowledge circulation based on demand-articulation within the business platform. In the basics, knowledge circulation starts with the learning needs and knowledge creation projects between the CoE S2M and companies. The project focuses on identifying the learning needs of the business platform. The implementation of knowledge creation projects is not part of this grant application but is an important pillar of the CoE S2M business model. Knowledge transfer takes place naturally through the teaching assistants. Education is ultimately responsible for knowledge valorisation in the form of a renewed and/or adapted training offer. The introduction of the learning company is the catalyst of the knowledge circulation. The learning company aims to provide an appropriate physical learning environment: from education through the Design Centre, in collaboration with the CoE S2M Partners through the developed on side learning environments or from the CoE S2M through the Smart Manufacturing Centre.