THE PROJECT PAIN-RELIFE AIMS TO CREATE A DYNAMIC AND INTEGRATED TECHNOLOGICAL ECOSYSTEM BASED ON BIG DATA MANAGEMENT AND ANALYSIS TECHNOLOGIES AIMED AT THE CONTINUITY OF PATIENT CARE WITH PAIN INVOLVING LÂINTERA HEALTH SUPPLY CHAIN, FROM DIAGNOSIS, HOME THERAPY, TELEMONITORING, PATIENT SUPPORT/CAREGIVER AND THAT ALLOWS TO SUPPORT THE PROCESS OF CHOICE (DECISION AID). ECOSYSTEM, IN ADDITION TO THE TECHNOLOGICAL COMPONENT, WILL ALSO GUARANTEE THE PRESENCE OF THE HUMAN FACTOR, SINCE THE THERAPEUTIC RELATIONSHIP WITH THE PATIENT, CAN NOT ONLY BE CONVEYED THROUGH TECHNOLOGICAL SOLUTIONS, HOWEVER INNOVATIVE, BUT ALSO PROVIDES AN INTERATION WITH A PROFESSIONAL FIGURE ABLE TO ENTER INTO CONNECTION WITH THE PERSON, GENERATE TRUST AND UNDERSTAND THE PERSONAL NEEDS THAT EACH PERSON/PATIENT HAS. PAIN-RELIFE WILL DEFINE BEST PRACTICES OF DATA REUSE, TAKING INTO ACCOUNT BOTH PRIVACY AND PROTECTION ISSUES