ENISIE intends to contribute to smart, sustainable and inclusive growth of the cross-border area moving from the field-based new generation social enterprise environment (innovative start-ups with a social vocation). It encourages the innovation in key areas such as digital health, food tech and sustainable tourism (experiential and seasonally adjusted), to foster the circular trans-border mobility of qualified young people and enable the internationalization of innovative SMEs from both sides of cross-border territories. Enisie aimed at providing immediate support in the post emergency COVID-19. The specific intent is to provide support, which can greatly help cover widespread needs as much as the recovery of economies in a new cross-border perspective through two strands of intervention. A prevalent part, consisting of accompanying services that will guarantee both the restoration of the business plan and the identification of the needs of the entities and companies within their reference sectors. A residual part represented by measures of direct and rapid support to companies and entities, through the provision of funds for a quick-impact project and small-scale project directly provided by the ENISIE project partners and aimed at covering the immediate needs of supplies and services to allow companies to overcome the crisis.