Nano-technologies and new materials (NMP) are a cornerstone of EU policy for innovation and advanced manufacturing. As one of the Key Enabling Technologies, the EU believes that NMP can reverse negative growth trends in manufacturing and foster growth and jobs. The statement is clear, but the road from intent to transfer, application and exploitation of NMP in manufacturing is long. NMP is dealt with in research. However, the common challenge is ensure that innovation actors cooperate to deliver research results to the manufacturing sector, with subsequent benefits for regional growth. NMP-REG groups partners from 5 regions, who want to face this challenge together. Their overall objective is to improve regional policies for delivery of innovation in NMP to manufacturing. NMP-REG focuses on policy actions that can support innovation delivery, using coordinated action from key players. Changes are particularly expected in projects funded by policy instruments (3 ERDF ROP / 2 other key policy tools for innovation), particularly in cluster support, financing for innovation actors and other horizontal innovation delivery measures. Partners also hope to influence policy management, in terms of monitoring and evaluation criteria for innovation delivery. NMP-REG achieves this through exchanging experiences and Good Practices in a context of interregional activities, communication and stakeholder engagement. Partners develop Action Plans that result in: improved policy instruments, more and better targeted funding, with leverage effect in mobilising private funding; new or improved models for innovation delivery thanks to cooperation across the regional innovation chain. All regional innovation players will benefit. NMP-REG works towards a medium/long-term impact of creating a regional system that can support the manufacturing sector in applying NMP research to create new products / services; create places of work; promote a market for improved and cost efficient products.