The EU telemedicine market is booming (€11.5 billion in 2019, annual growth rates of 13%). Within NWE, this industry is concentrated in NL, B, UK and D. In this market, eHealth is in its infancy when it comes to transferring hospital care from the hospital to the patients’ home. Currently, only 1 hospital (Isala) is executing this concept supported by 1 SME. Few supporting technologies are being developed (TRL2). An integrated technology package is missing to fully exploit economic potential. NWE-Chance aims at enabling co-creation of eHealth concepts for admitting heart failure patients at home. By combining the expertise of eHealth focussed companies, hospitals specialised in heart failure treatment and research institutes, a home hospitalisation platform will be developed which integrates a real time monitoring system with a nano-based test for measuring potassium and creatine and a wearable patch to monitor vital functions.Besides this development, NWE-Chance aims at setting up and Innovation Hub for supporting the industry in the NWE-region on the Long Term in the development, valorisation and implementation of new eHealth technologies which support home hospitalisation. NWE-Chance will support during the project 3 eHealth companies in further developing and validating their technologies accompanied by strategic recommendations for successful integration in treatment concepts, leading to 30 new jobs. The NWE-Chance Innovation Hub which will be established at the end of the project, will build on 10 new collaborations between SMEs and hospitals. Continued networking through the Hub has, after 5 years, involved 20 SMEs in collaborations with hospitals, 15 new digital innovations, leading to 120 new jobs. 10 years later, apart from a continuation of growth as mentioned above, new impact will be seen due to the acceptance of eHealth for hospital care at home in additional health sectors, thus establishing NWE as a serious region on eHealth devices.