The aim of the project is the technological modernisation and upgrade of the large research infrastructure BBMRI-CZ. The objectives of the project are fully in line with Call No 02_18_046 Research Infrastructures II, Specific Objective 1 (SC 1). Modernisation will lead to increased reproducibility of basic and translational research in the areas of investigation of processes of aetiopagenesis of cancer and other socially serious diseases across different fields of medicine.