THE PROJECT AIMS TO VALIDATE AND COMMERCIALISE INNOVATIVE SERVICES AND TOOLS FOR RESEARCH AND DIAGNOSTICS, IN THE FIELD OF FRET FLUORESCENCE MICROSCOPY, AIMED AT MEASURING PROTEIN-PROTEIN INTERACTIONS (PPIS) CONSIDERED BIOMARKERS FOR SYSTEMIC INFLAMMATORY PROCESSES, INCLUDING THOSE RELATED TO RHEUMATOID ARTHRITIS. IN THE CONTEXT OF THE DEVELOPMENT OF THE ABOVE PROJECT PROPOSAL, ALDA SRL WILL BE INVOLVED MAINLY IN THE PRODUCTION OF FLUORESCENT PROBES, DEVELOPMENT OF ALDA-TEST KITS FOR THE ANALYSIS OF CYTOKINE RECEPTORS AND ANALYSIS BY FRET MICROSCOPY OF PATIENT BLOOD SAMPLES AT THE EUROBIOIMAGING FACILITY IN NAPLES (ACTIVITIES 1 AND 3 DESCRIBED IN SECTION A1.2). THE UNIVERSITY BIO-MEDICAL CAMPUS OF ROME (UCBM) WILL PARTICIPATE IN THE PROJECT IN THE FIELD OF CLINICAL VALIDATION OF ALDA-TEST TECHNOLOGY (ACTIVITIES 2 AND ACTIVITIES 3 DESCRIBED IN SECTION A1.2) THROUGH THE RECRUITMENT OF PATIENTS TO BE INCLUDED IN THE CL STUDY