The objective of the INTENSIVE project is the characterisation of biological organisms by multimodal imageries and differential diagnostic system based on Artificial Intelligence. The identification of signatures of different tissues is a real challenge in a context of medical applications and in particular by the use of unsupervised approaches allowing in the long term to propose solutions for diagnosis and post-operative follow-up in situ without biopsy or manipulation of samples. In this context, it is necessary not only to integrate a societal dimension into this project but also to take into account legal and ethical issues.