The aim of the work is to develop “predictive” digital tools to assess the synergies between environmental factors (fluid flow, mechanical stresses) on the mechanical and/or physico-chemical resistance of materials. This section will assess the endurance of structures under combined or cyclic stresses. In order to carry out these actions, the research programme is structured around three axes: Durability of materials in high temperature, durability of structures in aggressive media and durability of metallic and organic coatings.