Proton therapy is a radiotherapy technique, aimed at irradiating cancerous tumors with a bundle of protons, particularly indicated in the treatment of tumors of children and adolescents. It also has many advantages in the treatment of so-called tumors of the base of the skull in adults, and some sarcomas. This treatment greatly reduces the long-term toxicity of radiation therapy. The project "Proton Radiation Therapy Center" aims to offer this therapeutic arsenal to patients in the AURA region. Phase 1 of the project, financed by the ERDF operation, will focus on the innovation of this project: the treatment of patients in a sitting or semi-standing position, thus ensuring better comfort during the treatment session by limiting the physiological movements of different organs. The installation of the vertical positioning system will allow, during phase 2, to install the clinical proton therapy equipment, as well as the parallel conduct of translational research. LCC will use the research results of this project to inform and improve manufacturing designs, software platforms, workflows, and clinical utility of its product line including proton and heavy ion therapy, photon and electron therapy, and diagnostic imaging.