The Occitanie Region, within the framework of its economic competence, is committed to VSE-SMEs by promoting their access to financing through unique funds in France. Since the JEREMIE programme, in the period 2007-2013, then FOSTER Languedoc-Roussillon and Midi-Pyrénées, in the period 2014-2020, the mobilisation of public funds, leveraging on private investment, has made it possible to support nearly 8000 companies in their creation or development projects. In particular, FOSTER has made it possible to raise investments amounting to €1.5 billion, i.e. a leverage effect of 28.4x on the regional contribution. The ex-ante study conducted in 2021 demonstrates the effectiveness of the FOSTER tools and highlights the financing needs of VSE-SMEs for the period 2021-2027, in a still very tense economic context. The establishment of a FOSTER 2 Fund, under the management of the European Investment Fund, will allow the continuation of regional support to more than 6,000 VSE-SMEs, a capacity of 600M€ to 800M€ of financing generated.