The aim of this project is to involve SMEs much more closely in the transition that the Leiden Bio Science Park (further LBSP) is making to an innovation district. While SMEs will be involved in all LBSP ambition themes, this application has chosen a specific focus within three work packages (WPs): 1) Activation of SMEs 2) Implementation of the LBSP-wide Human Capital Agenda; 3) Broad inclusion of innovation and valorisation in LSH education. The collaboration within this project is unique because the triple helix is represented at every level.