One in four people die from thrombosis. Biomarkers in the blood can predict the occurrence of thrombosis, but unfortunately there are currently no suitable methods to measure these biomarkers in the blood. Within this project, the solution, the PC200 measuring instrument, will be developed by collaboration of experts in the field of photonics, biochemistry and medical research. The PC200 can quickly and accurately measure platelet activity optically, at a fraction of the cost of existing biochemical measurement methods. The enormous potential of the PC200 forimproving the diagnosis, monitoring and treatment of these conditions will be tested and demonstrated. The project contributes to the mission of the RIS3 to enable a "longer healthy and happier life" and to reduce healthcare costs. In addition, this project makes a major contribution to the social objective of the OPZuid and the SDGs through the health gains that can be achieved with it.