The aim of the project is the development and preparation of nanofibrous 3D carriers, functionalized by biologically active substances separated in the form of endogenous stem cell material, as a medicinal product intended for the treatment of tendon damage and serious skin tissue injuries. As a comparative alternative, 3D bioprinting technology will be designed and created to enable the production of a wide range of specific biomaterials in the form of specially structured matrices designed also for the treatment of serious skin injuries.