Matrix stiffness as a major regulator of aggressiveness and clinical response of triple-negative breast cancer Metastases are the leading cause of cancer death and are related to extracellular matrix stiffness (ECM). Recently, we have linked protein recycling to the progression of MTNC and have shown that high levels of RES (a protein recycling regulator) predict the response to taxane-based chemotherapy. Now we will explore how protein recycling is influenced by the rigidity of MEC to identify new therapies.share on FacebookTwitterLinkedinEmailreport an issue
