The aim of the project is to develop new polymer-ceramic composite biomaterials for applications in bone regenerative medicine. The cooperation of all research teams will develop porous implants for bone tissue regeneration and bone stabilising implants covered with innovative coating materials. An innovative solution on the coating materials market will be a collagen coating containing both hydroxyapatite and the active substance, i.e. clindamycin. The breakthrough will be to obtain a composite implant of bone tissue, which will be characterised by the ability to stimulate bone cells by mechanotransduction and release clindamycin and factors: anti-inflammatory TGF-beta and VEGF growth.